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Index > Protein center > Trem2(Gene name) > Mouse
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  • Trem2 (Gene name),
  • Triggering receptor expressed on myeloid cells 2 (Protein name ),  TREM2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Trem2(Trem2a;Trem2b;Trem2c);
    Protein name:
    Triggering receptor expressed on myeloid cells 2(TREM-2);
    Alternative:
    Triggering receptor expressed on monocytes 2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with TYROBP/DAP12.
    Function:
    May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
    Subcellular Location:
    Isoform 2 Secreted
    Protein Attributes:
    Sequence length:
    227
    Sequence:
    50:
    MGPLHQFLLL | LITALSQALN | TTVLQGMAGQ | SLRVSCTYDA | LKHWGRRKAW | 
    100:
    CRQLGEEGPC | QRVVSTHGVW | LLAFLKKRNG | STVIADDTLA | GTVTITLKNL | 
    150:
    QAGDAGLYQC | QSLRGREAEV | LQKVLVEVLE | DPLDDQDAGD | LWVPEESSSF | 
    200:
    EGAQVEHSTS | RNQETSFPPT | SILLLLACVL | LSKFLAASIL | WAVARGRQKP | 
    227:
    GTPVVRGLDC | GQDAGHQLQI | LTGPGGT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    UniGene:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse TREM-2
    Cat.:
    E12753m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse TREM-2
    Cat.:
    E12753h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse TREM-2
    Cat.:
    U12753h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse TREM-2
    Cat.:
    U12753m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse TREM-2
    Polyclonal Antibody for Mouse TREM-2
    Cat.:
    P12753Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse TREM-2
    Monoclonal Antibody for Mouse TREM-2
    Protein for Mouse TREM-2
    Protein for Mouse TREM-2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes."
      Bouchon A. , Dietrich J. , Colonna M.
      J. Immunol.164:4991-4995(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Cloning and characterization of a novel mouse myeloid DAP12-associated receptor family."
      Daws M.R. , Lanier L.L. , Seaman W.E. , Ryan J.C.
      Eur. J. Immunol.31:783-791(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY;INTERACTION WITH TYROBP/DAP12
      strain: BALB/c.
      tissue: Macrophage.
    3. 3.
      "Heterogeneous expression of the triggering receptor expressed on myeloid cells-2 on adult murine microglia."
      Schmid C.D. , Sautkulis L.N. , Danielson P.E. , Cooper J. , Hasel K.W. , Hilbush B.S. , Sutcliffe J.G. , Carson M.J.
      J. Neurochem.83:1309-1320(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);TISSUE SPECIFICITY
      strain: C57BL/6J.
      tissue: Brain.
    4. 4.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Spinal cord.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT TRP-78
      strain: Czech II.
      strain: FVB/N.
      tissue: Lung.
      tissue: Mammary gland.
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